How to Clean Dog Pee off a Mattress Like a Pro

A mattress with a visible stain

Table of Contents

When you share your home with a canine companion, accidents are bound to happen. Whether you’re dealing with a new puppy, an aging pet, or a dog that’s feeling unwell, you may find yourself needing to clean up a mess on your mattress. Fortunately, with the right approach and a bit of elbow grease, you can remove the stain and odor, restoring your mattress to its former glory.

Understanding the Challenge

Before diving into the cleaning process, it’s important to understand why dog urine can be such a challenge to clean. First, urine is a complex substance that contains a variety of compounds. When it dries, it can leave a stubborn stain that’s difficult to remove. Second, urine has a strong, distinctive odor that can linger long after the visible stain has been cleaned. Finally, if not properly cleaned, the scent of urine can attract your dog back to the same spot, leading to repeat accidents.

Despite these challenges, it’s entirely possible to clean dog pee off a mattress effectively. The key is to act quickly, use the right products, and follow the correct procedures. Let’s explore how.

The Cleaning Process

Immediate Action

As soon as you discover the accident, it’s crucial to act quickly. The longer the urine sits, the more it will soak into the mattress, making it harder to clean. Here’s what to do:

  1. Blot the wet area with a clean, dry cloth or towel. Avoid rubbing, as this can spread the urine and push it deeper into the mattress.
  2. Remove any bedding and wash it separately. Use a laundry detergent that’s designed to break down proteins, as this will help to remove the urine.

Stain Removal

Once you’ve blotted up as much of the urine as possible, it’s time to tackle the stain. There are several methods you can use, depending on what you have available.

One of the most effective ways to clean dog pee off a mattress is to use an enzymatic cleaner. These cleaners contain special enzymes that break down the proteins in urine, effectively removing both the stain and the odor. Here’s how to use one:

  1. Spray the stained area with the enzymatic cleaner. Be sure to follow the instructions on the product label.
  2. Let the cleaner sit for the recommended amount of time. This allows the enzymes to do their work.
  3. Blot the area with a clean, dry cloth to remove the cleaner. Again, avoid rubbing.

If you don’t have an enzymatic cleaner on hand, you can make a homemade cleaning solution using vinegar and baking soda. Here’s how:

  1. Mix one part white vinegar with one part water. Spray or pour this solution onto the stained area.
  2. Let the solution sit for about 10 minutes. This gives the vinegar time to neutralize the urine.
  3. Blot the area with a clean, dry cloth to remove the solution.
  4. Sprinkle baking soda over the area. Let it sit for several hours, or overnight if possible.
  5. Vacuum up the baking soda. This should remove any remaining odor.

Odor Removal

Even after the stain is gone, you may still notice an odor. This is because urine can penetrate deep into the mattress, where it’s difficult to reach with surface cleaning methods. To remove the odor, you may need to use a specialized odor remover. These products are designed to neutralize the smell, rather than simply masking it.

Here’s how to use an odor remover:

  1. Spray the affected area with the odor remover. Be sure to follow the instructions on the product label.
  2. Let the product sit for the recommended amount of time.
  3. Blot the area with a clean, dry cloth to remove the product.

Preventing Future Accidents

Once you’ve successfully cleaned your mattress, you’ll want to take steps to prevent future accidents. Here are some tips:

  • Consider using a waterproof mattress protector. This can help to prevent urine from soaking into the mattress in the first place.
  • Regularly take your dog outside to pee. This can help to prevent accidents, especially with puppies or older dogs.
  • If your dog is repeatedly having accidents, it may be a sign of a health issue. Consult with your vet to rule out any medical problems.


Cleaning dog pee off a mattress can be a daunting task, but with the right approach, it’s entirely doable. By acting quickly, using the right products, and following the correct procedures, you can effectively remove both the stain and the odor. And by taking steps to prevent future accidents, you can help to keep your mattress clean and fresh for years to come.

Become a Cleaning Pro with

Don’t let pet accidents stress you out! With, you’ll have access to a wealth of knowledge that will turn any cleaning challenge into a simple task. Whether it’s dog pee on a mattress or any other spill, our expert advice is just a subscription away. Subscribe to our free email list today and get the pro tips, techniques, and special offers you need to tackle messes with confidence. Join the community and never wonder how to clean it ever again!

Was this article helpful?
Something seem wrong? Let us know. We rely on your reviews.